5 meanings: 1. the act of confusing or the state of being confused 2. disorder; jumble 3. bewilderment; perplexity 4. lack of.... Click for more definitions. Learn the meaning of confusion, a noun that describes a situation of not understanding or knowing what to do. See how to use confusion in sentences and find synonyms, collocations and translations. Learn about the causes, symptoms, types, and treatments for confusion. Understand when it's a sign of a serious condition and how to manage it effectively. Confusion is a symptom of brain activity disruptions that affects your memory, thinking, awareness and more. Learn about the possible causes, how to recognize confusion and when to seek medical help.