Desonide is a mild topical corticosteroid that helps reduce inflammation, itching, and redness on your skin. Think of it as a gentle, anti-inflammatory cream or ointment that calms down irritated skin without being too strong for sensitive areas like your face or skin folds. Desowen Cream is used in the treatment of Skin conditions with inflammation & itching. View Desowen Cream (tube of 10.0 gm Cream) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg.com Desonide is a steroid that helps reduce inflammation in the body. Desonide topical (for the skin) is used to treat inflammation and itching caused by eczema or skin conditions that respond to steroid medication. Desonide topical may also be used for purposes not listed in this medication guide. Desonide is used to treat skin problems such as redness, itching and swelling. It is generally prescribed for mild to moderate atopic dermatitis (eczema), seborrheic dermatitis, and contact dermatitis.