The Double Marker Test is a blood test performed between 11 to 14 weeks of pregnancy to evaluate the risk of chromosomal abnormalities in fetus like Down syndrome. Learn about its importance, procedure and reports during pregnancy. One diagnostic tool is called the double marker test , which involves giving blood to be analyzed for markers of certain chromosomal abnormalities. Here’s more about how and when the test is... Learn about the Double Marker Test in pregnancy , its uses, test results, procedures, and normal range values. Understand the dual marker test report and its significance. What is a Double Marker Test ? The Double Marker Test , also known as the dual marker test is a blood screening that checks for 2 major substances in the mother’s blood sample. The test is generally recommended between the 9th and 12th weeks of pregnancy .