HOLISTIC meaning : 1. dealing with or treating the whole of something or someone and not just a part: 2. dealing with…. Learn more. Holistic means dealing with or treating the whole of something or someone and not just a part. Learn more about the meaning , usage, and pronunciation of holistic with examples from the Cambridge English Corpus. A holistic approach takes into account the broader context, diverse influences, and intricate dynamics that shape the subject of consideration. It involves considering physical, emotional, mental, and spiritual aspects when assessing well-being, problem-solving, or analysis. Holistic definition : incorporating the concept of holism, or the idea that the whole is more than merely the sum of its parts, in theory or practice.. See examples of HOLISTIC used in a sentence.