Medscape - Indication-specific dosing for MgSO4 (magnesium sulfate), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost... Magnesium Sulphate Injection is a medicine used in the treatment of decreased magnesium levels in blood. It is also used for treatment of seizures in pregnant women who have high blood pressure. It widens the blood vessels in the brain and improves the blood supply to the nerve cells. Magnesium sulfate is used as a laxative to relieve occasional constipation. Magnesium sulfate (Epsom salt) can also be added to a bath for use as a soaking solution to help relieve minor sprains and bruises. Not all external uses for magnesium sulfate have been approved by the FDA. Magnesium sulfate is a salt with the formula MgSO4 , consisting of magnesium cations and sulfate anions. It is a white crystalline solid, soluble in water, and has many uses in agriculture, medicine, and industry.