A mucocele is a fluid-filled swelling that occurs inside the mouth, commonly on the lower lip, tongue, floor of the mouth, or inner cheeks. It develops due to the blockage or rupture of a salivary gland duct, causing mucus to accumulate and form a soft, painless lump. An ophthalmic plastic and orbital perspective on ethmoidal frontal sinus mucoceles. Mucoceles are benign, recurrent mucus-filled cysts that can be mildly painful. You can try medical treatment and self-care tips for timely relief. WebMD explains the causes, symptoms, and treatment of a mucocele -- a type of cyst that forms in your mouth when salivary glands become blocked.