Name Clavulanate potassium Drug Entry Clavulanic acid Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. 8 Clavulanic acid is derived from the organism Streptomyces clavuligerus. 1 When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav, or ... However, Potassium Clavulanate is more commonly used in clinical practice due to its formulation advantages. Understanding the attributes of Clavulanic Acid and Potassium Clavulanate is essential for healthcare professionals to make informed decisions regarding their use in combination with antibiotics. Clavulanate Potassium is a semi-synthetic beta-lactamase inhibitor isolated from streptomyces. Clavunalate potassium contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. This protects other beta-lactam antibiotics from beta-lactamase catalysis. Amoxicillin and Clavulanate Potassium is an oral antibacterial combination consisting of amoxicillin and the beta‑lactamase inhibitor, clavulanate potassium (the potassium salt of clavulanic ...
