The sustained release (SR) tablet formulation currently marketed contains progesterone in a methyl- cellulose base which hydrates in the gastrointestinal tract providing a slow release matrix for a gradual release of progesterone [14]. Susten 200 MG Tablet SR is a medicine that contains natural micronised progesterone , a female hormone. It is used to treat irregular menstruation and prevent uterine cancer. Learn about its uses, side effects, dosage, price, composition, and more. Progesterone sustained release tablets 300 mg are medication that slowly releases progesterone into the bloodstream. They help regulate menstrual cycles, support early pregnancy, and treat hormone imbalances. Susten SR 300 Tablet is used to treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. It contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body. This medicine may sometimes cause side effects such as dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint ...