Pus cells in urine, or pyuria, are a sign of infection or inflammation in the urinary tract. Learn about the causes, symptoms, and treatment of pus cells in urine, and how to test for them with a urinalysis. Pus cells in urine, or pyuria, can be a sign of infection, inflammation, or other health issues. Learn about the normal range, the possible causes, the symptoms, the diagnosis methods, and the treatment options for pus cells in urine. Pus cells in urine analysis, also known as pyuria, refer to the presence of white blood cells or leukocytes in a person's urine sample. These cells are an important diagnostic marker in urinalysis and are typically a sign of an underlying health condition, most commonly a urinary tract infection (UTI). While the normal range of white blood cells in urine is low, an elevated count of pus cells suggests inflammation and infection in the urinary tract. In some cases, pyuria can also indicate ... Pus cells are white blood cells (WBCs) that help your body fight infections. When they’re found in your urine, it usually means your immune system is responding to something going wrong in your urinary tract — like an infection or inflammation. This condition is medically known as pyuria. In small numbers, pus cells in urine can be harmless. But a high count? That often means there’s a bigger issue that needs your attention.