Explore the que sera, sera meaning, an idiom signifying fate's role in life . Jump right into its origin, various meanings, and examples in this quick guide. The phrase “que sera sera” is often used in casual conversations, texts, and social media posts to convey a sense of acceptance for things that are uncertain or out of one’s control. The meaning of QUE SERÁ, SERÁ is what will be, will be. They changed it to que sera , sera because American audiences were more familiar with Spanish. Read Que Sera , Sera : Translation & Meaning Lesson