Parkinson's disease is an illness that affects the part of your brain that controls how you move your body. It can come on so slowly that you don't even notice it at first. Parkinson’s disease is a brain disorder that affects movement and causes tremor, stiffness, and slowness. It results from the loss of dopamine-producing nerve cells in the brain and may have genetic and environmental factors. Parkinson's disease is a movement disorder of the nervous system that worsens over time. The nervous system is a network of nerve cells that controls many parts of the body, including movement. Parkinson disease (PD) is a brain condition that causes problems with movement, mental health, sleep, pain and other health issues. It has no cure, but therapies and medicines can reduce symptoms. Learn about the causes, symptoms, diagnosis, treatment, impact and WHO response to PD.