Wilson disease is an inherited disorder in which excessive amounts of copper accumulate in the body, particularly in the liver, brain, and eyes. Explore symptoms, inheritance, genetics of this condition. Overview of Wilson disease symptoms, which may affect the liver, nervous system, eyes, or other organs. Autosomal recessive gene mutations cause Wilson disease . The WDA aspires to unmask the challenges of Wilson disease and unleash the promise of a cure. The Causes of Wilson's Disease Wilson's Disease is an autosomal recessive genetic disorder caused by mutations in the ATP7B gene. This mutation impairs the body's ability to remove excess copper, leading to its accumulation in vital organs such as the liver, brain, and eyes. Under normal circumstances, the liver processes dietary copper and excretes the excess through bile. In individuals with Wilson's Disease , this pathway is disrupted, resulting in toxic copper buildup. The genetic nature ...
