What are the uses of amlodipine? Amlodipine is an antihypertensive medication used to treat hypertension (high blood pressure), angina (chest pain), and coronary artery disease (narrowing or blockage of coronary arteries, the major blood vessels of the heart, caused by the buildup of fatty material called plaque). Amlodipine works by relaxing the blood vessels, improving blood flow, and thereby lowering the blood pressure, effectively relieving the strain on the heart. Lowering blood ... Amlodipine is a calcium channel blocker used to treat high blood pressure, angina, arrhythmia and other conditions. Learn about its working, common side effects, available medicines and expert advice on 1mg.com. Amlodipine is a prescription medication that is used with or without other medications to treat high blood pressure. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems. Amlodipine is used alone or together with other medicines to treat hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.