Amyloidosis: Amyloidosis is a clinical disorder caused by

Amyloidosis Amyloidosis is a clinical disorder caused by extracellular and/or intracellular deposition of insoluble, abnormal amyloid fibrils that alter the normal function of tissues. [5] Only 10% of amyloidosis deposits consist of components such as glycosaminoglycans (GAGs), apolipoprotein E (apoE), and serum amyloid P-component (SAP), while nearly 90% of the deposits consist of amyloid fibrils that are formed by the aggregation of misfolded proteins. These proteins either arise from ... Amyloidosis is a rare disease in which abnormally folded proteins form into collections called amyloid fibrils that accumulate in various tissues and organs, sometimes leading to organ dysfunction, organ failure, and death. Amyloidosis is a rare disease caused by abnormal protein deposits. Learn about its symptoms, diagnosis, treatment options, and management for better health outcomes. Amyloidosis is a rare disease that causes abnormal protein deposits in the body's organs. Learn about the different types, signs, tests and therapies for this condition from Johns Hopkins Medicine.