Learn how the body prevents excessive bleeding when a blood vessel is injured. Find out the roles of platelets, clotting factors, and fibrin in the blood clotting process and its disorders. Blood is a necessary component of the human body, and the loss of this fluid may be life-threatening. Blood is generated via hematopoiesis and ultimately becomes the delivery method for oxygen to the tissues and cells. The human body protects against loss of blood through the clotting mechanism. Vascular mechanisms, platelets, coagulation factors, prostaglandins, enzymes, and proteins are the contributors to the clotting mechanism which act together to form clots and stop a loss of blood ... What is the Clotting of Blood ? Blood clotting or clotting of blood , which also refers to the process called haemostasis, is the formation of a gel-like or clot-like structure, preventing bleeding or loss of blood , i.e., haemorrhage in cases of injured blood vessels. In this article we will discuss about the mechanisms and stages of blood clotting . Mechanism of Blood Clotting : Blood Clotting is one of three mechanisms that reduce the loss of blood from broken blood vessels. The three Mechanisms are: i. Vascular Spasm: The smooth muscle in blood vessel walls contracts immediately the blood vessel is broken. This response reduces blood loss for some time, while the other haemostatic mechanisms become active. ii. Platelet Plug Formation: When blood ...