Explore the causes of chest pain , from GERD to heart conditions, and discover treatment options to find relief and protect your health. Chest pain can be caused by your heart, lungs, muscles, bones and even skin . Learn how to know if chest pain is serious and when to get help. Does the location of chest pain matter? You may be wondering why your chest is hurting if you have pain on the right side or middle of your chest and whether it’s a sign of a heart attack. Chest pain that comes and goes has numerous possible origins, including the heart, muscles, and lungs. This article discusses possible causes .