Clindamycin gel or Clindamycin phosphate gel is a topical gel antibiotic used to treat acne. It works by stopping the growth of acne-causing bacteria and reducing skin inflammation. It is often prescribed by dermatologists and is helpful for people who haven't had success with acne treatments. Due to the emergence of resistant strains of P acnes,staphylococci and the known anti-inflammatory effects of nicotinamide , topically applied clindamycin phosphate 1 % alone was compared with clindamycin phosphate gel I% and nicotinamide gel 4% in combination in the treatment of moderate acne vulgaris. Materials and Methods. Clindamycin + nicotinamide is used in the treatment of acne. The detailed uses of Clindamycin + nicotinamide are as follows: • Acne Treatment: Clindamycin + nicotinamide is frequently used to treat acne by reducing skin bacteria and irritation, which helps prevent new outbreaks. Clindamycin is an antibiotic which works by penetrating into the skin and killing acne-causing bacteria. Nicotinamide is a form of vitamin B. It exerts anti-inflammatory effects when applied to the skin and reduces swelling, redness and tenderness associated with acne.
