The meaning of ERGONOMICS is an applied science concerned with designing and arranging things people use so that the people and things interact most efficiently and safely —called also biotechnology, human engineering, human factors. How to use ergonomics in a sentence. Ergonomics can roughly be defined as the study of people in their working environment. More specifically, an ergonomist (pronounced like economist) designs or modifies the work to fit the worker, not the other way around. Something that is designed to work smoothly with the human body is designed to be ergonomic . If your fingers ache after using the computer, you may need an ergonomic keyboard. Or you could play fewer video games. Ergonomics impact us all — whether we realize it or not. Read on to learn about the definition, domains and applications of ergonomics and how the science of ergonomics impacts your world at work, at home, and all the places in between.