History of Holi: Holi, also called the Festival of Colors, is a joyful and ancient Hindu festival celebrated in India and other parts of the world. It marks the victory of good over evil, based on the story of Prahlada and his father, Hiranyakashipu. According to legend, Hiranyakashipu wanted to harm his son for worshipping Lord Vishnu. Abstract Linear ubiquitin chains, which are generated specifically by the linear ubiquitin assembly complex (LUBAC) ubiquitin ligase, play crucial roles in immune signaling, including NF-κB activation. LUBAC comprises catalytic large isoform of heme-oxidized iron regulatory protein 2 ubiquitin ligase 1 ( HOIL -1L) interacting protein (HOIP), accessory HOIL -1L, and SHANK-associated RH domain-interacting protein (SHARPIN). Deletion of the ubiquitin ligase activity of HOIL -1L, an accessory ... होली भारत का अत्यंत प्राचीन पर्व है जो होली, होलिका या होलाका [6] नाम से मनाया जाता था। वसंत की ऋतु में हर्षोल्लास के साथ मनाए जाने के कारण इसे वसंतोत्सव और काम-महोत्सव भी कहा गया है। राधा-श्याम ... Holi (IPA: ['hoːli:, hoːɭiː]) is a major Hindu festival celebrated as the Festival of Colours, Love and Spring. [1][7][8][9] It celebrates the eternal and divine love of the deities Radha and Krishna. [10][11] Additionally, the day signifies the triumph of good over evil, [12][13] as it commemorates the victory of Vishnu as Narasimha over Hiranyakashipu. [14][15] Holi originated and is predominantly celebrated in the Indian subcontinent, but has also spread to other regions of Asia and ...

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