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Ibuprofen Ibuprofen is a pain reliever, belonging to the non-steroidal anti-inflammatory class of drugs. It is pretty much a popular medicine and helps in the treatment of inflammation, pain, fever (by lowering the body temperature), etc. It usually blocks the production of prostaglandins, which are the ones that promote pain, fever, and inflammation. Medicine has much more to it. Let us start by discussing its uses in detail. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Learn about the side effects of ibuprofen, from common to rare, for consumers and healthcare professionals. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID), pain reliever and fever reducer used to temporarily relieve minor aches and pains. Ibuprofen is generally considered safe when taken as directed.