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Lose definition: to come to be without (something in one's possession or care), through accident, theft, etc., so that there is little or no prospect of recovery.. See examples of LOSE used in a sentence. The Difference between ‘ Lose ’ and ‘Loose’ – Meanings The easiest way to remember when to use ‘ lose ’ and ‘loose’ appropriately in a sentence is to know their meanings. The term ‘lost’ is the past form of the verb ‘ lose ’, which simply means to misplace or leave behind something. It also means to be deprived of something, for example, ‘You will lose all the fear once you do it’, but when you use the word ‘loose’ as an adjective, it means ill-fitting or not tied ... ' Lose ' is a verb referring to the act of no longer possessing or misplacing something, while ' loose ' is an adjective describing something that is not tight or firmly attached. Learn the meaning, pronunciation, and examples of the verb lose , which means to be unsuccessful in retaining possession of something or to suffer deprivation. Compare lose with loose and find related words and phrases.