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MALIGNANT definition : 1. A malignant disease or growth is cancer or is related to cancer, and is likely to be harmful…. Learn more. A term used to describe cancer. Malignant cells grow in an uncontrolled way and can invade nearby tissues and spread to other parts of the body through the blood and lymph system. For something that's very harmful, especially a tumor that's cancerous, use the term malignant . “ Malignant ” is a term used to describe active cancer cells or tumors. This is a general term, however, and may be applied to any condition that is serious enough to lead to a person’s death.
