Ondansetron is used to prevent vomiting and nausea. Ondansetron is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery. 2.3 Administration Instructions for ZOFRAN ODT Orally Disintegrating Tablets Do not attempt to push ZOFRAN ODT tablets through the foil backing. With dry hands, PEEL BACK the foil backing of 1 blister and GENTLY remove the tablet. IMMEDIATELY place the ZOFRAN ODT tablet on top of the tongue where it will dissolve in seconds, then swallow with saliva. Administration with liquid is not necessary. Find patient medical information for Ondansetron (Zofran, Zofran ODT, Zuplenz) on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings Ondansetron is indicated for the prevention of nausea and vomiting associated with: Ondansetron is also indicated for the prevention of postoperative nausea and/or vomiting. The recommended dosage regimens for adult and pediatric patients are described in Table 1 and Table 2, respectively.

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