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Orchitis is an acute inflammatory reaction of the testis secondary to infection. Most cases are associated with a viral mumps infection; however, other viruses and bacteria can cause orchitis . Testicular orchitis consists of an inflammatory process of the male gonad due to trauma to the testicles or a bacterial or viral infection. This alteration can cause male sterility and, therefore, must be treated. Orchitis causes symptoms that can affect daily life. Learn about treatment options available to help manage and improve quality of life. Orchitis is an inflammation caused in one or both testicles. It can be the result of a bacterial infection. The mumps virus can also cause orchitis .