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Abstract Paracetamol (PAR), phenylephrine hydrochloride (PHE) and chlorpheniramine maleate (CPM) are commonly used in clinical practice as antipyretic and analgesic drugs to ameliorate pain and fever in cold and flu conditions. The present work describes the use of thermal analysis for the characterization of the physicochemical compatibility between drugs and excipients during the development of solid dosage forms. Thermogravimetric analysis (TGA) and Differential Scanning Calorimetry (DSC ... A mix of three medicines—chlorpheniramine maleate, paracetamol, and phenylephrine HCL—helps relieve the symptoms of a common cold. In doctors’ offices, medicines like paracetamol (PAR), phenylephrine hydrochloride (PHE), and chlorpheniramine maleate (CPM) are often used to help with pain and fever when someone has the flu or a cold. Chlorpheniramine Maleate + Paracetamol + Phenylephrine is used to relieve cold and flu symptoms such as fever, nasal congestion, headache, and sore throat. It may cause drowsiness, so caution is advised during activities needing alertness. Paracetamol (PAR), phenylephrine hydrochloride (PHE) and chlorpheniramine maleate (CPM) are commonly used in clinical practice as antipyretic and analgesic drugs to ameliorate pain and fever in cold and flu conditions. The present work describes the use of thermal analysis for the characterization of the physicochemical compatibility between drugs and excipients during the development of solid dosage forms. Thermogravimetric analysis (TGA) and Differential Scanning Calorimetry (DSC) were ...
