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Autopsy vs. Post-Mortem: A Comparative Analysis Autopsy and post-mortem are terms often used interchangeably, yet they hold distinct meanings within the fields of forensic science, medicine, and law. Both procedures involve examining a deceased body to determine the cause of death, but they differ in their scope, purpose, and context. The meaning of POSTMORTEM is done, occurring, or collected after death. How to use postmortem in a sentence. POST MORTEM definition: 1. happening or taken after a person or animal dies: 2. a medical examination of a dead person's…. Learn more. A post-mortem, also known as an autopsy, is the examination of a body after death. The aim of a post-mortem is to determine the cause of death.