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Peptide bond, disulfide bond, their nomenclature, and their characteristics, along with the primary structure of proteins and their importance, are described. Learn about the primary structure of proteins, which is the sequence of amino acids in a polypeptide chain. Also, explore the secondary, tertiary and quaternary structures of proteins and their formation and examples. To understand how a protein gets its final shape or conformation, we need to understand the four levels of protein structure: primary, secondary, tertiary, and quaternary. The simplest level of protein structure, primary structure, is simply the sequence of amino acids in a polypeptide chain. A protein’s primary structure is the unique sequence of amino acids in each polypeptide chain that makes up the protein. Because the final protein structure ultimately depends on this sequence, this is called the primary structure of the polypeptide chain.