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Learn about bilirubin , a yellow pigment formed from red blood cell breakdown, and how to measure it in blood, urine or amniotic fluid. Find out the causes and symptoms of high or low bilirubin levels in adults and newborns. Learn what bilirubin is, how it affects your liver and bile, and what a bilirubin test measures. Find out what high or low bilirubin levels mean and how to interpret your test results. A bilirubin test measures the amount of bilirubin in your blood. It's used to help find the cause of health conditions like jaundice, anemia, and liver disease. What does it mean to have high bilirubin ? We’ll go over the meaning, symptoms, and causes of high bilirubin levels, as well as how to treat it.