What are Stevens – Johnson syndrome and toxic epidermal necrolysis? Stevens – Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are now believed to be variants of the same condition, distinct from erythema multiforme. SJS/TEN is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal ... Stevens- Johnson syndrome (SJS) is a serious skin condition that causes rashes, blisters and peeling due to an allergic reaction to medications or infections. Learn about the risk factors, diagnosis, complications and prevention of SJS and how to get dermatology care. Stevens – Johnson syndrome (SJS) is a type of severe skin reaction. [1] Together with toxic epidermal necrolysis (TEN) and Stevens – Johnson /toxic epidermal necrolysis (SJS/TEN) overlap, they are considered febrile mucocutaneous drug reactions and probably part of the same spectrum of disease, with SJS being less severe. [1][5][3] Erythema ... Excerpt Previously known as Lyell syndrome , Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome , and other drug eruptions.