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Researchers at Queen Elizabeth College, University of London, discovered sucralose in 1976, during a collaborative research program with UK sugar producer, Tate & Lyle, PLC. Sucralose is made by a multi-step process that starts with ordinary table sugar (sucrose) and replaces three hydrogen-oxygen groups on the sugar molecule with three chlorine atoms. This results in a stable sweetener that tastes like sugar, but is calorie-free. After being discovered, sucralose was put through a ... Sucralose is a low-calorie artificial sweetener made from sugar. Learn about its potential effects on weight, gut health, blood sugar and more from a registered dietitian. Sucralose is an artificial sweetener that is found in thousands of products. Find out what you need to know about sucralose and your health. Sucralose is a food additive initially used to mitigate glycemic peaks and calorie intake in patients with diabetes and obesity. Although sucralose has been considered safe for human consumption, the World Health Organization (WHO) issued a global alert in 2023 concerning the potential health implications of this artificial sweetener. This review aims to comprehensively explore the effects of sucralose intake on human health by understanding sucralose absorption, metabolism, and excretion ...