Sumatriptan , sold under the brand name Imitrex among others, is a medication used to treat migraine headaches and cluster headaches. [4][1] It is taken orally, intranasally, or by subcutaneous injection. [5] Therapeutic effects generally occur within three hours. [5] Sumatriptan is a serotonin (5-HT1B/1D) receptor agonist (triptan). [1] The drug acts as a serotonin 5-HT 1B, 5-HT 1D, and 5-HT 1F receptor agonism [6][7] and its common side effects include chest pressure, fatigue, vomiting ... Abstract:- Sumatriptan , a selective serotonin 5-HT1 receptor agonist, is widely used for the acute treatment of migraine and cluster headaches. This review explores the pharmacological profile, efficacy, safety, and clinical applications of sumatriptan , as well as its role within the broader class of triptans. Sumatriptan ’s mechanism of action primarily involves the constriction of cranial blood vessels, inhibition of pro-inflammatory neuropeptide release, and modulation of trigeminal ... Sumatriptan is approved by the U.S. Food and Drug Administration (FDA) as an abortive treatment for migraine attacks in adults, both with and without aura. Administering sumatriptan via the subcutaneous route can offer relief for acute episodes of cluster headaches. Based on clinical studies, sumatriptan is an effective and well-tolerated treatment for migraines when administered intravenously, subcutaneously, or orally. The medication is also used to alleviate symptoms of photophobia ... Sumatriptan is a drug that treats acute migraine headache by constricting blood vessels in the head and blocking pain signals. Find out more about its uses, side effects, drug interactions and available medicines on 1mg, India's largest healthcare platform.
