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We would like to show you a description here but the site won’t allow us. Learn about the significance, cost, and side effects of Vitamin B12 test, and the normal range of 200-600 pg/mL in blood. Find out the symptoms and causes of high and low Vitamin B12 levels, and how to treat them. Optimal levels: The optimal vitamin B12 levels are generally considered to be between 400 and 600 pg/mL. It is important to note that vitamin B12 levels can fluctuate depending on various factors, including diet, health conditions, and the use of supplements. Learn more about vitamin B12 test, its normal range, and what high or low levels suggest. Discover the causes & symptoms of a deficiency, and medical attention.