Xylazine:

Xylazine , or 'tranq,' is a new lethal drug on the streets. Understand its effects, potential risks, and the impact of this tranquilizer on mental health. Xylazine , or tranq, is increasingly being mixed with drugs like fentanyl or heroin and can be difficult to detect. Most people who use drugs are unable to tell if they have been exposed to it. Xylazine is an extremely lipophilic compound with a half-life ranging from 23 to 50 minutes in various animal models (2). Its duration of action may be extended because of absorption and redistribution from adipose tissue. Xylazine ’s lipophilic nature and its action on various receptors underscore the risk for dangerous drug-drug interactions, especially with opioids such as the synthetic opioid fentanyl (11). Xylazine may mitigate noradrenergic withdrawal symptoms during acute use ... Xylazine , or “tranq,” is a sedative that can slow vital functions and cause overdose. Learn about its effects, risks, and how to respond to an overdose involving xylazine .