Endemic Diseases. Epidemics Vs Endemics. Hyperendemic Disease and Hypoendemic Disease. Examples and Control of Endemic Diseases. Endemic definition: natural to or characteristic of a specific people or place; native; indigenous.. See examples of ENDEMIC used in a sentence. Explore the meaning and history of the word ' endemic .' Find detailed explanations, synonyms, and antonyms, along with practical examples. Endemic means especially of a disease or a condition, regularly found and very common among a particular group or in a particular area. Learn more about the usage, synonyms, antonyms, and translations of endemic with Cambridge Dictionary.